| Procedure For Handling Of Power Failure In Microbiology Department. |
1.0 OBJECTIVE To lay down a Procedure for handling of power failure in microbiology department. 2.0 SCOPE This procedure is handling of power failure in microbiology applicable for all instrument/equipment in the Quality Control Department of Microbiology Area. 3.0 RESPONSIBILITY • Microbiologist : for reporting to head of department for handling of power failure in microbiology. • Head of concern area : To participate investigation of power failure and product quality. 4.0 ACCOUNTABILITY • Department Head To Read this SOP Click Here SOP for Entry and Exit in Microbiology Testing Area. 5.0 PROCEDURE 5.1 General guideline 5.1.1 In case of power failure/UPS interruption, stop the analysis on instrument/equipment immediately, quarantine all analytical solution. 5.1.2 Inform to Head-Micro, QC and Engineering Department regarding the failure of power/UPS by phone or SMS. 5.1.3 After getting confirmation form engineering department, restart the instrument/equipment as per respective standard operating procedure. 5.1.4 Head-QC shall categorize critical and non-critical instruments/equipment depending upon system suitability requirements and impact on analysis. 5.2 Types of instrument/equipment’s 5.2.1 Analytical balance 5.2.2 pH meter 5.2.3 laminar Air Flow 5.2.4 Stability Chamber 5.2.5 BOD incubator 5.2.6 Heating block 5.2.7 Autoclave 5.3 Analytical balance and pH Meter: – If USP failure occurred during weighing or measurement of pH , then re-plan weighing/measurement after calibration of the instruments. 5.4 TOC: If UPS failure occurred during analysis, then invalidate graphs/prints out with proper justification and plan analysis with same solution/sample. 5.5 Laminar air flow: If USP failure occurred during analysis, stop the analysis immediately and wait for UPS supply. After UPS supply, restart LAF for 10minutes and clean surface with 70% IPA. If UPS failure occurred during pipetting of sample discard the same plate and prepare new plate. Close the led of exposed plated which were previously exposed during LAF validation and expose new plates. If negative control plant before UPS failure and the analysis is not finished, then prepare a new negative control plate after getting UPS supply. 5.6 In case of critical instrument/equipment, review the power failure or UPS failure impact on analysis. 5.7 Refrigerators: if UPS failure occurred, ensure that temperature reading are within the acceptance criteria. If temperature reading are not within the acceptance criteria, then proceed as per respective SOP. 5.8 Autoclave: if power/UPS failure occurred during sterilization at 115°c, if temperature drops below the 114°c, then discard the media, write remark in log book and plan analysis with fresh media preparation and sterilization. If power/UPS failure during sterilization at 121°c, if temperature drops below 120.9°c then restart the autoclave and continue sterilization in case of HPHV cycle and in case of media cycle stop the activity, discard the media, write a remark in log book and plan analysis with fresh media preparation and sterilization 5.9 BOD incubator: if power/UPS failure occurred, ensure that temperature/humidity (whichever applicable) readings are within the acceptance criteria. If temperature reading are not within the acceptance criteria, then proceed as per respective SOP. 5.10 Heating block: – if power/UPS failure occurred during analysis, then invalidated the analysis and plan analysis with fresh solution/sample. |
