| Method of analysis for Hydrochloric Acid IP |
| 1.0 PROCEDURE 1.1 Sampling and Handling 1.1.1 Quantity for composite sample for analysis Hydrochloric Acid IP, HCl, MW. 36.5 For chemical analysis: 200 ml 1.1.2 Reanalysis Period of Hydrochloric Acid Two year. 1.2 Physical and Chemical Testing 1.2.1 Description A Clear, colourless, fuming liquid; odour, pungent. Pour about 2.0 gram. of sample of HCl in a clean dry Petri dish and observed with unaided eye observed. 1.2.2 Solubility Miscible Soluble with water : 1.0gm. in 1 millilitre purified water To read this method of analysis click here Method of analysis for Lactic Acid IP. 1.2.3 Bromide and iodide Dilute 5 ml with 10 ml of water, add 1 ml of chloroform and, dropwise with constant shaking, chlorinated lime solution; the chloroform layer does not become brown or violet. 1.2.4 Free chlorine To 15 ml, add 100 ml of carbon dioxide-free water, 1 ml of a 10% w/v solution of potassium iodide and 0.5 ml of starch solution and allow to stand in the dark for 2 minutes. Any blue colour produced disappears on the addition of 0.2 ml of 0.01M sodium thiosulphate. 1.2.5 Sulphite Dilute 1 ml with 10 ml of water and add 0.25 ml of barium chloride solution and 1 ml of 0.01M iodine; the colour of the iodine is not completely discharged. 1.2.6 Residue on evaporation Evaporate 100 gm to dryness on a water-bath and dry the residue to constant weight at 105 degree Celsius. Weight of the residue = Final weight (W2) – Initial weight (W1) Residue = Residue weight x 100 / Sample Volume 1.2.7 Assay of Hydrochloric Acid Weigh accurately about 2 g, add 30 ml of water, mix and titrate with 1M sodium hydroxide using methyl red solution as indicator. Each ml of 1M sodium hydroxide is equivalent to 0.03646 g of HCl. Purity of HCl = Vol. cons. of 1M NaOH x Factor x Actual molarity x 100 / Sample weight x State Molarity |
